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Article

Variability in loss of constitutional heterozygosity across loci and among individuals: association with candidate genes in ductal breast carcinoma.

Molecular carcinogenesis - 1 Nov 1996

Rebbeck T R, Godwin A K, Buetow K H

Abstract excerpt

Genes involved in the metabolic activation or detoxification of environmental carcinogens may contribute to breast cancer susceptibility by influencing rates of somatic mutation. To examine this hypothesis, we studied the association between loss of constitutional heterozygosity (LOH) in ductal breast tumors and allelic variability in genes that regulate the metabolism of environmental carcinogens. LOH was...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8944071
DOI: 10.1002/(SICI)1098-2744(199611)17:3<117::AID-MC3>3.0.CO;2-C

Genes

NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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