Article
Loss of heterozygosity on the long arm of chromosome 6 in breast cancer: possibly four regions of deletion.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Sept 1996
Noviello C, Courjal F, Theillet C
Abstract excerpt
Deletions and rearrangements involving chromosome 6q have been reported in a number of human cancers such as ovarian and breast tumors as well as melanoma and hemopoietic malignancies. To gain insight into the regions undergoing deletions on the long arm of chromosome 6, we performed a survey of loss of heterozygosity (LOH) at 11 CA repeat markers, mapping from 6q13 to 6q27 in 83 matched sets of tumor and blood...
Topics
- Alleles
- Breast Neoplasms
- Chromosome Deletion
- Chromosomes, Human, Pair 6
- DNA, Neoplasm
- Dinucleotide Repeats
- Female
- Genetic Markers
- Humans
- Loss of Heterozygosity
- Middle Aged