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Increased risk of local recurrence is associated with allelic loss in normal lobules of breast cancer patients.

Cancer research - 15 Feb 2002

Li Zheng, Moore Dan H, Meng Zhen Hang, Ljung Britt-Marie, Gray Joe W, Dairkee Shanaz H

Abstract excerpt

Allelic losses characteristic of tumor cells, when displayed by morphologically normal terminal ductal lobular units (TDLUs) adjacent to carcinoma [G. Deng et al., Science (Wash. DC), 274: 2057-2059, 1996], may indicate an extended field of increased cancer susceptibility within the affected breast tissue. We investigated this possibility by asking whether the presence of loss of heterozygosity (LOH) at...

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PMID: 11861372

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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