Article
Accurate genotyping from paraffin-embedded normal tissue adjacent to breast cancer.
Carcinogenesis - 1 Feb 2006
Xie Bin, Freudenheim Jo L, Cummings Simone S, Singh Baljit, He Hong, McCann Susan E, Moysich Kirsten B, Shields Peter G
Abstract excerpt
Genetic polymorphism analysis for disease risk is widely used in epidemiology studies; blood or oral cavity cells are the most widely used source of DNA. However, these types of samples are not always available, particularly for studies that were conducted years ago. An alternative potential source of patient DNA exists in the form of paraffin-embedded normal tissue adjacent to tumor samples, which are collected...
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