Article
Cancer classification using loss of heterozygosity data derived from single-nucleotide polymorphism genotyping arrays.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference - 1 Jan 2000
Wang Yuhang
Abstract excerpt
Single-Nucleotide Polymorphism (SNP) array is a recently introduced technology that genotypes more than 10,000 human SNPs on a single array. It has been shown that genome-wide Loss of Heterozygosity (LOH) calls can be derived by analyzing the genotypes calls measured by SNP arrays using paired tumor and normal tissue samples. The goal of this study is to evaluate the possibility of cancer classification using LOH...
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