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Article

DPY-26, a link between dosage compensation and meiotic chromosome segregation in the nematode.

Science (New York, N.Y.) - 6 Dec 1996

Lieb J D, Capowski E E, Meneely P, Meyer B J

Abstract excerpt

The DPY-26 protein is required in the nematode Caenorhabditis elegans for X-chromosome dosage compensation as well as for proper meiotic chromosome segregation. DPY-26 was shown to mediate both processes through its association with chromosomes. In somatic cells, DPY-26 associates specifically with hermaphrodite X chromosomes to reduce their transcript levels. In germ cells, DPY-26 associates with all meiotic...

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Identifiers

PMID: 8939869
DOI: 10.1126/science.274.5293.1732

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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DPY-26, a link between dosage compensation and meiotic chromosome segregation in the nematode.PMID 8939869Read ↗

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Unexpected role for dosage compensation in the control of dauer arrest, insulin-like signaling, and FoxO transcription factor activity in Caenorhabditis elegans.Semantic proximity Read ↗

Condensin IDC has a functional ATPase that is required for X-Chromosome dosage compensation in C. elegans.Semantic proximity Read ↗

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