Article
Unexpected role for dosage compensation in the control of dauer arrest, insulin-like signaling, and FoxO transcription factor activity in Caenorhabditis elegans.
Genetics - 1 Jul 2013
Dumas Kathleen J, Delaney Colin E, Flibotte Stephane, Moerman Donald G, Csankovszki Gyorgyi, Hu Patrick J
Abstract excerpt
During embryogenesis, an essential process known as dosage compensation is initiated to equalize gene expression from sex chromosomes. Although much is known about how dosage compensation is established, the consequences of modulating the stability of dosage compensation postembryonically are not known. Here we define a role for the Caenorhabditis elegans dosage compensation complex (DCC) in the regulation of...
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