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Article

Developmental Dynamics of X-Chromosome Dosage Compensation by the DCC and H4K20me1 in C. elegans.

PLoS genetics - 1 Dec 2015

Kramer Maxwell, Kranz Anna-Lena, Su Amanda, Winterkorn Lara H, Albritton Sarah Elizabeth, Ercan Sevinc

Abstract excerpt

In Caenorhabditis elegans, the dosage compensation complex (DCC) specifically binds to and represses transcription from both X chromosomes in hermaphrodites. The DCC is composed of an X-specific condensin complex that interacts with several proteins. During embryogenesis, DCC starts localizing to the X chromosomes around the 40-cell stage, and is followed by X-enrichment of H4K20me1 between 100-cell to comma...

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Identifiers

PMID: 26641248
DOI: 10.1371/journal.pgen.1005698
PMCID: PMC4671695

Genes

DCC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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