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Article

Active maintenance of meiosis-specific chromosome structures in Caenorhabditis elegans by the deubiquitinase DUO-1.

Proceedings of the National Academy of Sciences of the United States of America - 24 Mar 2026

Strand Liesl G, Choi Charlotte P, McCoy Savannah, Nsamba Emmanuel T, Silva Nicola, Villeneuve Anne M

Abstract excerpt

Meiotic prophase is characterized by a dynamic program in which germ cells undergo a complex series of associations and dissociations of protein complexes that drive assembly, remodeling, and disassembly of meiosis-specific chromosome structures and dramatic changes in chromosome compaction. Failure to properly coordinate these processes can result in improper chromosome segregation, producing aneuploid gametes...

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Share to Caenorhabditis elegans Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41838919
DOI: 10.1073/pnas.2532671123
PMCID: PMC13012089

Genes

USP26
USP29

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PubMed metadata and Literature Corpus relationships.

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