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Article

The dpy-30 gene encodes an essential component of the Caenorhabditis elegans dosage compensation machinery.

Genetics - 1 Aug 1994

Hsu D R, Meyer B J

Abstract excerpt

The need to regulate X chromosome expression in Caenorhabditis elegans arises as a consequence of the primary sex-determining signal, the X/A ratio (the ratio of X chromosomes to sets of autosomes), which directs 1X@A animals to develop as males and 2X/2A animals to develop as hermaphrodites. C. elegans possesses a dosage compensation mechanism that equalizes X chromosome expression between the two sexes despite...

Topics

Animals
Caenorhabditis elegans
Dosage Compensation, Genetic
Female
Genes, Helminth
Genes, Lethal
Helminth Proteins
Male
Phenotype
Sex Determination Analysis
X Chromosome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7982580
DOI: 10.1093/genetics/137.4.999
PMCID: PMC1206076

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7982580-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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