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Article

The dpy-30 gene encodes an essential component of the Caenorhabditis elegans dosage compensation machinery.

Genetics - 1 Aug 1994

Hsu D R, Meyer B J

Abstract excerpt

The need to regulate X chromosome expression in Caenorhabditis elegans arises as a consequence of the primary sex-determining signal, the X/A ratio (the ratio of X chromosomes to sets of autosomes), which directs 1X@A animals to develop as males and 2X/2A animals to develop as hermaphrodites. C. elegans possesses a dosage compensation mechanism that equalizes X chromosome expression between the two sexes despite...

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Identifiers

PMID: 7982580
DOI: 10.1093/genetics/137.4.999
PMCID: PMC1206076

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Source receipt: pubmed, retrieved 7 Sept 2026.

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