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Article

Dosage compensation proteins targeted to X chromosomes by a determinant of hermaphrodite fate.

Science (New York, N.Y.) - 11 Jun 1999

Dawes H E, Berlin D S, Lapidus D M, Nusbaum C, Davis T L, Meyer B J

Abstract excerpt

In many organisms, master control genes coordinately regulate sex-specific aspects of development. SDC-2 was shown to induce hermaphrodite sexual differentiation and activate X chromosome dosage compensation in Caenorhabditis elegans. To control these distinct processes, SDC-2 acts as a strong gene-specific repressor and a weaker chromosome-wide repressor. To initiate hermaphrodite development, SDC-2 associates...

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Source

Identifiers

PMID: 10364546
DOI: 10.1126/science.284.5421.1800

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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