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Article

Allelic loss at chromosome 13q12-q13 is associated with poor prognosis in familial and sporadic breast cancer.

British journal of cancer - 1 Nov 1996

van den Berg J, Johannsson O, Håkansson S, Olsson H, Borg A

Abstract excerpt

Loss of heterozygosity (LOH) was analysed in 84 primary tumours from sporadic, familial and hereditary breast cancer using five microsatellite markers spanning the chromosomal region 13q12-q13 which harbours the BRCA2 breast cancer susceptibility gene, and using one other marker located within the RBI tumour-suppressor gene at 13q14. LOH at the BRCA2 region was found in 34% and at RBI in 27% of the tumours....

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Source

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Identifiers

PMID: 8932343
DOI: 10.1038/bjc.1996.597
PMCID: PMC2074869

Genes

BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Allelic loss at chromosome 13q12-q13 is associated with poor prognosis in familial and sporadic breast cancer.PMID 8932343Read ↗

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Patterns of loss of heterozygosity at loci from chromosome arm 13q suggests a possible involvement of BRCA2 in sporadic breast tumors.Semantic proximity Read ↗

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