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Article

Altered phenotype of HT29 colonic adenocarcinoma cells following expression of the DCC gene.

Oncogene - 22 Apr 1999

Velcich A, Corner G, Palumbo L, Augenlicht L

Abstract excerpt

On 18q, frequently deleted in late stage colorectal cancers, a gene, Deleted in Colon Cancer (DCC), has been identified and postulated to play a role as a tumor suppressor gene. DCC is retained in the majority of mucinous tumors, which produce high levels of mucins, and seems to be preferentially expressed in intestinal goblet cells. To investigate whether DCC is related to mucin expression and can modulate the...

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Source

Identifiers

PMID: 10353603
DOI: 10.1038/sj.onc.1202610

Genes

DCC
MUC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Altered phenotype of HT29 colonic adenocarcinoma cells following expression of the DCC gene.PMID 10353603Read ↗

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The DCC Protein and Prognosis in Colorectal CancerSemantic proximity Read ↗

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