Apolipoprotein E genotyping in sporadic amyotrophic lateral sclerosis: evidence for a major influence on the clinical presentation and prognosis.

doi:10.1016/0022-510x(96)00085-8

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Article

Apolipoprotein E genotyping in sporadic amyotrophic lateral sclerosis: evidence for a major influence on the clinical presentation and prognosis.

Journal of the neurological sciences - 1 Aug 1996

Moulard B, Sefiani A, Laamri A, Malafosse A, Camu W

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative motor neuron disorder of unknown etiology. Recently, in Alzheimer's disease (AD) apolipoprotein E (APOE) alleles have been shown to play an important role in disease phenotype. To determine whether APOE have a similar influence in other n...

Topics

Age of Onset
Aged
Alleles
Amyotrophic Lateral Sclerosis
Apolipoproteins E
Female
Gene Frequency
Genotype
Humans
Male
Middle Aged
Prognosis
Sex Factors
Survival Analysis

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