Article
[The role of apolipoprotein E in patients with amyotrophic lateral sclerosis (a clinical and genetic study)].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2009
Kutakova E V, Zakharova M N, Illarioshkin S N, Kliushnikov S A, Zavalishin I A, Ivanova-Smolenskaia I A
Abstract excerpt
The apolipoprotein E (apoE) gene plays an important role in forming predisposition and modulating the course of Alzheimer's disease, primary parkinsonism and some other human neurodegenerative disorders. In this study, for the first time in the Russian population, we performed the analysis of genetic association of apoE gene variants in 62 patients with a sporadic form of amyotrophic lateral sclerosis (ALS) aged...
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