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Article

Does apolipoprotein E genotype modify the clinical expression of ALS?

European journal of neurology - 1 Apr 2011

Jawaid A, Poon M, Strutt A M, Rice L K, McDowell E J, Salamone A R, Qureshi S U, Simpson E, Appel S H, York M K, Schulz P E

Abstract excerpt

BACKGROUND: The presence of the apolipoprotein E (ApoE) 4 genotype is associated with an earlier age of onset for Alzheimer's disease (AD) and several other neurodegenerative disorders. The objective of this study was to investigate the effect of ApoE genotypes on the clinical course of amyotrophic lateral sclerosis (ALS). METHODS: Eight hundred and fifty-two consecutive patients with sporadic ALS evaluated at a...

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Identifiers

PMID: 20880000
DOI: 10.1111/j.1468-1331.2010.03225.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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