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Article

Apolipoprotein E epsilon 4 allele is not associated with earlier age at onset in amyotrophic lateral sclerosis.

Annals of neurology - 1 Sept 1995

Mui S, Rebeck G W, McKenna-Yasek D, Hyman B T, Brown R H

Abstract excerpt

Apolipoprotein E allele 4 (apo E epsilon 4) is known to be in genetic disequilibrium with Alzheimer's disease and is associated with an earlier age at onset of dementia. Whether apo E epsilon 4 is a specific risk factor for Alzheimer's disease or is a more general susceptibility factor that shift...

Topics

Age of Onset
Alleles
Amyotrophic Lateral Sclerosis
Apolipoprotein E4
Apolipoproteins E
Base Sequence
Genotype
Humans
Molecular Sequence Data
Superoxide Dismutase

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7668834
DOI: 10.1002/ana.410380318

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7668834-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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