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Article

Lack of association between APOE gene polymorphisms and amyotrophic lateral sclerosis: a comprehensive meta-analysis.

Amyotrophic lateral sclerosis & frontotemporal degeneration - 1 Dec 2014

Govone Flora, Vacca Alessandro, Rubino Elisa, Gai Annalisa, Boschi Silvia, Gentile Salvatore, Orsi Laura, Pinessi Lorenzo, Rainero Innocenzo

Abstract excerpt

Several studies have evaluated the association between APOE gene polymorphisms and the risk for amyotrophic lateral sclerosis (ALS), with inconclusive results. The aim of our study was to further define the risk associated with carriage of the APOE alleles and development and clinical characteristics of ALS. We performed a comprehensive meta-analysis of all existing studies investigating the association between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24918518
DOI: 10.3109/21678421.2014.918149

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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