Prognostic significance of the p53 mutation in esophageal cancer.

doi:10.1093/oxfordjournals.jjco.a023234

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Article

Prognostic significance of the p53 mutation in esophageal cancer.

Japanese journal of clinical oncology - 1 Oct 1996

Uchino S, Saito T, Inomata M, Osawa N, Chikuba K, Etoh K, Kobayashi M

Abstract excerpt

In the esophagus, alterations in the p53 tumor suppressor gene are associated with the development of preinvasive neoplastic lesions to invasive carcinoma. The role of p53 gene mutation in the progression of esophageal cancer still remains unclear. In this study, 82 DNA samples extracted from for...

Topics

Esophageal Neoplasms
Genes, p53
Humans
Mutation
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Prognosis

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