Prognostic value of p53 mutations in oesophageal adenocarcinoma: final results of a 15-year prospective study.

doi:10.1016/j.ejcts.2009.12.018

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Article

Prognostic value of p53 mutations in oesophageal adenocarcinoma: final results of a 15-year prospective study.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery - 1 Jun 2010

Madani Koroush, Zhao Ronghua, Lim Hyun Ja, Casson Alan G

Abstract excerpt

OBJECTIVE: This study evaluates the clinical significance of p53 mutations in oesophageal adenocarcinoma (EADC). METHODS: Between February 1991 and February 2006, 142 consecutive patients with EADC underwent potentially curative oesophageal resection. No patient received induction therapy. Strict clinicopathologic criteria were used to define primary EADC (Type I), excluding gastric cardia adenocarcinoma (Type...

Topics

Adenocarcinoma
Adult
Aged
Aged, 80 and over
Biomarkers, Tumor
Epidemiologic Methods
Esophageal Neoplasms
Esophagectomy
Female
Genes, p53
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Mutation

Neoplasm Staging

Prognosis

Treatment Outcome

Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 20227286
DOI: 10.1016/j.ejcts.2009.12.018

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