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Article

The p53 gene mutation is of prognostic value in esophageal squamous cell carcinoma patients in unified stages of curability.

American journal of surgery - 1 Jun 1999

Kobayashi S, Koide Y, Endo M, Isono K, Ochiai T

Abstract excerpt

BACKGROUND: The p53 gene alteration is identified in approximately half of all human tumors, and is now thought to be a key gene for regulating the cell cycle through the induction of p21(WAF1/CIP1) and inducing apoptosis through some genes such as BAX. In this study, we investigated the prognostic value of p53 mutation for postoperative esophageal squamous cell carcinoma patients. METHODS: The subjects studied...

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Share to Carcinoma, Squamous Cell
Share to Esophageal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, p53

Share to Polymerase Chain Reaction

Share to Polymorphism, Single-Stranded Conformational

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Source

Identifiers

PMID: 10414702
DOI: 10.1016/s0002-9610(99)00085-9

Genes

BAX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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