Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation of the p53 gene predicts lymph node metastases in Japanese patients with esophageal carcinoma: DNA and immunohistochemical analyses.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus - 1 Jan 2003

Hattori K, Kajiyama Y, Tsurumaru M

Abstract excerpt

We evaluated the clinicopathologic significance of p53 gene mutations, including a comparison of DNA analysis and immunohistochemical examination, in Japanese patients with esophageal squamous cell carcinoma, a highly aggressive cancer. Genomic DNA isolated from 76 tumors without preoperative treatment was subjected to polymerase chain reaction and sequencing. Associations were sought between p53 mutations and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Esophageal Neoplasms

Share to Genes, p53

Share to Immunohistochemistry

Share to Lymphatic Metastasis

Share to Predictive Value of Tests

Source

Identifiers

PMID: 14641293
DOI: 10.1111/j.1442-2050.2003.00351.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutation of the p53 gene predicts lymph node metastases in Japanese patients with esophageal carcinoma: DNA and immunohistochemical analyses.PMID 14641293Read ↗

Prognostic significance of the p53 mutation in esophageal cancer.Semantic proximity Read ↗

High prevalence of p53 protein overexpression in patients with esophageal cancer in Linxian, China and its relationship to progression and prognosis.Semantic proximity Read ↗

[The relationship between p53 mutation and esophageal cancer biological behavior].Semantic proximity Read ↗

Prevalence and predictive value of p53 mutation in patients with oesophageal squamous cell carcinomas: a prospective clinico-pathological study and survival analysis of 70 patients.Semantic proximity Read ↗

p53 gene mutations in esophageal squamous cell carcinoma and their relevance to etiology and pathogenesis: results in Japan and comparisons with other countries.Semantic proximity Read ↗

Genetic and immunohistochemical analyses of p53 independently predict regional metastasis of gastric cancers.Semantic proximity Read ↗

Clinical implications of p53 tumor suppressor gene mutation and protein expression in esophageal adenocarcinomas: results of a ten-year prospective study.Semantic proximity Read ↗

Role of p53 gene mutations in human esophageal carcinogenesis: results from immunohistochemical and mutation analyses of carcinomas and nearby non-cancerous lesions.Semantic proximity Read ↗

K-ras and p53 gene mutations in colorectal cancer in 57 Japanese patients.Semantic proximity Read ↗

The p53 gene mutation is of prognostic value in esophageal squamous cell carcinoma patients in unified stages of curability.Semantic proximity Read ↗

[Clinical significance of mutant p53 protein expression in lung adenocarcinoma].Semantic proximity Read ↗

Prevalence of p53 mutations and protein expression in esophageal cancers in southern Thailand.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.