Article
In vivo footprinting and high-resolution methylation analysis of the mouse hypoxanthine phosphoribosyltransferase gene 5' region on the active and inactive X chromosomes.
Molecular and cellular biology - 1 Nov 1996
Litt M D, Hornstra I K, Yang T P
Abstract excerpt
To investigate potential mechanisms regulating the hypoxanthine phosphoribosyltransferase (HPRT) gene by X-chromosome inactivation, we performed in vivo footprinting and high-resolution DNA methylation analysis on the 5' region of the active and inactive mouse HPRT alleles and compared these resu...
Topics
- 3T3 Cells
- Alleles
- Animals
- Base Sequence
- Cell Line
- Chromosome Mapping
- Conserved Sequence
- DNA Footprinting
- DNA Methylation
- Humans
- Hypoxanthine Phosphoribosyltransferase
- Mice
- Molecular Sequence Data
- Muridae
- Polymerase Chain Reaction
- Sequence Homology, Nucleic Acid
- X Chromosome