Article
Inactive allele-specific methylation and chromatin structure of the imprinted gene U2af1-rs1 on mouse chromosome 11.
Genomics - 1 Jul 1996
Shibata H, Yoshino K, Sunahara S, Gondo Y, Katsuki M, Ueda T, Kamiya M, Muramatsu M, Murakami Y, Kalcheva I, Plass C, Chapman V M, Hayashizaki Y
Abstract excerpt
The imprinted U2af1-rs1 gene that maps to mouse chromosome 11 is predominately expressed from the paternal allele. We examined the methylation of genomic sequences in and around the U2af1-rs1 locus to establish the extent of sequence modifications that accompanied the silencing of the maternal al...
Topics
- Alleles
- Animals
- Chromatin
- Chromosome Mapping
- CpG Islands
- Crosses, Genetic
- Female