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Article

Hypomutable potential accompanying interferon-alpha resistance in a human cell line, IFr, derived from interferon-alpha-sensitive and hypermutable RSa cells.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Sept 1996

Suzuki N, Suzuki H, Ishizuka T, Yamamori H, Takakubo Y

Abstract excerpt

A human cell line, IFr, established from RSa cells, is a variant with increased resistance to cell proliferation inhibition (CPI) by human interferon (HuIFN)-alpha. The parent RSa cells are also hypermutable after irradiation with far-ultraviolet light (UV), as assessed by two different methods: cloning efficiency of ouabain-resistant (OuaR) mutants and K-ras codon 12 mutation in genomic DNA identified by...

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Identifiers

PMID: 8887058
DOI: 10.1089/jir.1996.16.733

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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