Article
Human cell clones, RSa and UVr-1, differing in their capability for UV-induced virus reactivation and phenotypic mutation.
Mutation research - 15 Apr 1994
Suzuki N, Kimoto H, Koseki H, Miura N, Watanabe T, Inaba N, Takamizawa H, Hashizume S
Abstract excerpt
UVr-1 is a human cell clone established as a variant with increased resistance to cell killing by ultraviolet light (UV, principally 254 nm wavelength) from a UV-sensitive cell clone, RSa. Both cells have been characterized to have much the same capacity of UV-induced DNA repair synthesis in whole cells, and the parent RSa cells were recently found to be hypermutable. In the present study UVr-1 cells were...
Topics
- Cell Cycle
- Clone Cells
- DNA Repair
- Humans
- Mutation
- Simplexvirus
- Ultraviolet Rays
- Vaccinia virus
- Virus Activation