Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

<b>Loss of heterozygosity studies at the retinoblastoma and breast cancer susceptibility (BRCA2) loci in pituitary, parathyroid, pancreatic and carcinoid tumours</b>

1 Aug 1996

Abstract excerpt

OBJECTIVE: Allelic deletion of the retinoblastoma (Rb) gene on chromosome 13 has been reported in both pituitary and parathyroid tumours. We have investigated the roles of the Rb and the hereditary breast cancer susceptibility gene (BRCA2), which lie within 25 cM of each other on chromosome 13q12-14, in the multi-step aetiology of endocrine tumours. PATIENTS AND MEASUREMENTS: Seventy-seven endocrine tumours (43...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Parathyroid Disorders and Treatments
Share to Pituitary Gland Disorders and Treatments
Share to Thyroid Cancer Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8881452
DOI: 10.1046/j.1365-2265.1996.d01-1561.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

<b>Loss of heterozygosity studies at the retinoblastoma and breast cancer susceptibility (BRCA2) loci in pituitary, parathyroid, pancreatic and carcinoid tumours</b>PMID 8881452Read ↗

Analysis of the retinoblastoma tumour suppressor gene in pancreatic endocrine tumours.Semantic proximity Read ↗

Frequent loss of heterozygosity at the retinoblastoma susceptibility gene (RB) locus in aggressive pituitary tumors: evidence for a chromosome 13 tumor suppressor gene other than RB.Semantic proximity Read ↗

A reappraisal of the Rb1 gene abnormalities in the diagnosis of parathyroid cancerSemantic proximity Read ↗

Loss of heterozygosity in sporadic breast tumours at the BRCA2 locus on chromosome 13q12-q13.Semantic proximity Read ↗

Mutational analyses of RB and BRCA2 as candidate tumour suppressor genes in parathyroid carcinomaSemantic proximity Read ↗

Molecular studies of loss of heterozygosity in Chinese sporadic retinoblastoma patients.Semantic proximity Read ↗

Human pituitary adenomas infrequently contain inactivation of retinoblastoma 1 gene and activation of cyclin dependent kinase 4 gene.Semantic proximity Read ↗

Chromosome 3p allele loss in early invasive breast cancer: detailed mapping and association with clinicopathological featuresSemantic proximity Read ↗

Allelic deletion in pituitary adenomas reflects aggressive biological activity and has potential value as a prognostic marker.Semantic proximity Read ↗

Loss of heterozygosity is detected at chromosomes 1p35-36 (NB), 3p25 (VHL), 16p13 (TSC2/PKD1), and 17p13 (TP53) in microdissected apocrine carcinomas of the breast.Semantic proximity Read ↗

Identification of allelic losses in benign, borderline, and invasive epithelial ovarian tumors and correlation with clinical outcome.Semantic proximity Read ↗

The functional loss of the retinoblastoma tumour suppressor is a common event in basal-like and luminal B breast carcinomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.