Analysis of the retinoblastoma tumour suppressor gene in pancreatic endocrine tumours.

doi:10.1046/j.1365-2265.1997.2861110.x

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Article

Analysis of the retinoblastoma tumour suppressor gene in pancreatic endocrine tumours.

Clinical endocrinology - 1 Nov 1997

Chung D C, Smith A P, Louis D N, Graeme-Cook F, Warshaw A L, Arnold A

Abstract excerpt

OBJECTIVES: The molecular pathogenesis of human pancreatic endocrine tumours (PETs) is largely unknown. One attractive candidate gene for involvement in pancreatic endocrine neoplasia is the retinoblastoma (Rb) tumour suppressor gene. A deletion of the Rb gene was recently described in a human in...

Topics

Adenoma, Islet Cell
Adolescent
Adult
Aged
Aged, 80 and over
Alleles
Female
Gastrinoma
Gene Deletion
Genes, Retinoblastoma
Genetic Markers
Humans
Insulinoma
Male
Middle Aged
Pancreatic Neoplasms

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