Article
Identification of allelic losses in benign, borderline, and invasive epithelial ovarian tumors and correlation with clinical outcome.
Cancer - 1 Oct 1997
Saretzki G, Hoffmann U, Röhlke P, Psille R, Gaigal T, Keller G, Höfler H, Löning T, Petersen I, Dietel M
Abstract excerpt
BACKGROUND: The somatogenetic alterations that lead to the development of benign adenomas, borderline tumors, and invasive ovarian carcinomas are not well understood. This study investigated allelic losses in these three types of ovarian tumors. METHODS: Twelve genetic regions on chromosomes 2q, 5q, 6p, 6q, 9p, 11q, 17p, 17q, 18q, and 22q were analyzed by polymerase chain reaction for loss of heterozygosity...
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