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Article

Allelic deletion in pituitary adenomas reflects aggressive biological activity and has potential value as a prognostic marker.

The Journal of clinical endocrinology and metabolism - 1 Mar 1997

Bates A S, Farrell W E, Bicknell E J, McNicol A M, Talbot A J, Broome J C, Perrett C W, Thakker R V, Clayton R N

Abstract excerpt

Tumors of the pituitary gland are usually benign adenomas and account for 10% of all intracranial neoplasms. Five pituitary tumors have previously been reported to harbor multiple allelic deletions. Of these, three displayed particularly aggressive biological behavior, whereas there were no clini...

Topics

Adenoma
Adolescent
Adult
Aged
Alleles
Biomarkers
Chromosome Mapping
Female
Gene Deletion
Heterozygote
Humans
Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Neoplasm Invasiveness

Pituitary Neoplasms

Prognosis

Source

Identifiers

PMID: 9062489
DOI: 10.1210/jcem.82.3.3799

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9062489-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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