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Molecular studies of loss of heterozygosity in Chinese sporadic retinoblastoma patients.

Clinica chimica acta; international journal of clinical chemistry - 1 Aug 2005

Zhang Xiao L, Fu Wei L, Zhao Hong X, Zhou Lai X, Huang Jun F, Wang Jiang H

Abstract excerpt

BACKGROUND: Retinoblastoma, an embryonic neoplasm of retinal origin, is the most common and severe intra-ocular tumor affecting infants and young children. METHODS: Loss of heterozygosity (LOH) on chromosome 13 was investigated in 16 Chinese sporadic RB patients, using 14 microsatellite markers spanning the complete chromosome 13, to determine whether those alterations different from the alteration of RB1 gene on...

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PMID: 15921673
DOI: 10.1016/j.cccn.2005.02.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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