Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clonal heterogeneity in human esophageal squamous cell carcinomas on DNA analysis.

Japanese journal of cancer research : Gann - 1 Sept 1996

Hori H, Miyake S, Akiyama Y, Endo M, Yuasa Y

Abstract excerpt

Cancers are thought to arise through multistep accumulation of somatic mutations in the progeny of a single cell. Multiple mutations may induce molecular intratumor heterogeneity. Therefore, we examined molecular clonal heterogeneity in esophageal squamous cell carcinomas. Twenty-four esophageal squamous cell carcinomas and associated lymph node metastases were examined for microsatellite alterations, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clone Cells
Share to DNA, Neoplasm
Share to Gene Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, p53

Share to Heterozygote

Share to Mutation

Share to Polymerase Chain Reaction

Share to Polymorphism, Single-Stranded Conformational

Source

Open in PubMed Open full text

Identifiers

PMID: 8878454
DOI: 10.1111/j.1349-7006.1996.tb02121.x
PMCID: PMC5921211

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clonal heterogeneity in human esophageal squamous cell carcinomas on DNA analysis.PMID 8878454Read ↗

Somatic mutations detected by mini- and microsatellite DNA markers reveal clonal intratumor heterogeneity in gastrointestinal cancers.Semantic proximity Read ↗

Molecular clonality analysis of esophageal adenocarcinoma by multiregion sequencing of tumor samples.Semantic proximity Read ↗

Heterogeneity of p53 mutational status in esophageal squamous cell carcinoma.Semantic proximity Read ↗

Loss of heterozygosity analysis shows monoclonal evolution with frequent genetic progression and divergence in esophageal carcinosarcoma.Semantic proximity Read ↗

Multiple squamous cell carcinomas of the head and neck show different phenotypes of allelic loss patterns suggesting different clonal origin of carcinogenesis.Semantic proximity Read ↗

Intratumor genetic heterogeneity in advanced human colorectal adenocarcinoma.Semantic proximity Read ↗

Intratumor genomic heterogeneity in breast cancer with clonal divergence between primary carcinomas and lymph node metastases.Semantic proximity Read ↗

Genetic progression and divergence in superficial esophageal squamous cell carcinoma by loss of heterozygosity analysis.Semantic proximity Read ↗

The origins of multiple squamous cell carcinomas in the aerodigestive tract.Semantic proximity Read ↗

Intratumor genetic heterogeneity and head and neck cancer relapse.Semantic proximity Read ↗

Evidence for limited molecular genetic heterogeneity as defined by allelotyping and clonal analysis in nine metastatic breast carcinomas.Semantic proximity Read ↗

Persistence of genetically altered fields in head and neck cancer patients: biological and clinical implications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.