Article
Genetic progression and divergence in superficial esophageal squamous cell carcinoma by loss of heterozygosity analysis.
Oncology reports - 1 Oct 2006
Shima Hideyuki, Hiyama Toru, Tanaka Shinji, Yoshihara Masaharu, Arihiro Koji, Chayama Kazuaki
Abstract excerpt
Esophageal squamous cell carcinoma (SCC) is one of the most common fatal carcinomas worldwide and has some of the most malignant characteristics among gastrointestinal tumors. Although a high frequency of loss of heterozygosity (LOH) for various genes has been observed in esophageal SCCs, these findings do not provide any information regarding the genetic pathways that may underlie the development and progression...
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