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Article

Multiple squamous cell carcinomas of the head and neck show different phenotypes of allelic loss patterns suggesting different clonal origin of carcinogenesis.

Anticancer research - 1 Jan 2000

Shiga Kiyoto, Ogawa Takenori, Yoshida Fumiaki, Matsuura Kazuto, Tateda Masaru, Saijo Shigeru, Miyagi Taeko, Kobayashi Toshimitsu

Abstract excerpt

BACKGROUND: Multiple squamous cell carcinomas in the head and neck are not such a rare phenomenon in patients. To examine if these tumors have the same genetic basis or not, we investigated genetic alterations such as allelic loss in such multiple tumors to see if they showed identical patterns. MATERIALS AND METHODS: Patterns of the loss of heterozygosity at 3p, 9p and 17p loci were analyzed in multiple head and...

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PMID: 14666696

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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