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Article

Loss of heterozygosity analysis shows monoclonal evolution with frequent genetic progression and divergence in esophageal carcinosarcoma.

Human pathology - 1 Mar 2004

Matsumoto Toshiharu, Fujii Hiroaki, Arakawa Atsushi, Yamasaki Shigetaka, Sonoue Hiroshi, Hattori Kimiaki, Kajiyama Yoshiaki, Hirose Sachiko, Tsurumaru Masahiko

Abstract excerpt

Carcinosarcoma (spindle cell carcinoma) of the esophagus is a rare neoplasm that shows squamous cell carcinoma (SCC) with a variable component of spindle cell sarcoma. Clinical and pathologic features of this neoplasm have been well documented, but the histogenesis has long been a matter of speculation and dispute. In an attempt to clarify the clonality and genetic relationships in the evolution of this neoplasm,...

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Identifiers

PMID: 15017588
DOI: 10.1016/j.humpath.2003.02.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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