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Article

Intratumor genetic heterogeneity in advanced human colorectal adenocarcinoma.

International journal of cancer - 1 Aug 2001

Baisse B, Bouzourene H, Saraga E P, Bosman F T, Benhattar J

Abstract excerpt

Colorectal carcinogenesis is widely accepted as one of the best-characterized examples of stepwise progression. The existing colorectal carcinogenesis model assumes genetic homogeneity of individual tumors for the main known genetic alterations: K-ras and p53 genes point mutations and loss of heterozygosity (LOH) of chromosome 5q and 18q. The object of the present study was to demonstrate the existence of an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11433398
DOI: 10.1002/ijc.1343

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APC
DCC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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