Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Persistence of genetically altered fields in head and neck cancer patients: biological and clinical implications.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 2001

Tabor M P, Brakenhoff R H, van Houten V M, Kummer J A, Snel M H, Snijders P J, Snow G B, Leemans C R, Braakhuis B J

Abstract excerpt

In 1953, Slaughter et al. [D. P. Slaughter et al., Cancer (Phila.), 6: 963-968, 1953] proposed the concept of field cancerization in patients with squamous cell carcinoma of the head and neck (HNSCC) and discussed its clinical significance for the development of second primary tumors and local re...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biopsy
Share to Carcinoma, Squamous Cell
Share to Chromosomes, Human, Pair 17

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 3

Share to Chromosomes, Human, Pair 9

Share to Head and Neck Neoplasms

Share to Loss of Heterozygosity

Share to Mucous Membrane

Source

Identifiers

PMID: 11410486

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11410486-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Persistence of genetically altered fields in head and neck cancer patients: biological and clinical implications.PMID 11410486Read ↗

Genetically altered fields as origin of locally recurrent head and neck cancer: a retrospective study.Semantic proximity Read ↗

Multiple head and neck tumors frequently originate from a single preneoplastic lesion.Semantic proximity Read ↗

A genetic explanation of Slaughter's concept of field cancerization: evidence and clinical implications.Semantic proximity Read ↗

Investigating a case of possible field cancerization in oral squamous cell carcinoma by the use of next-generation sequencing.Semantic proximity Read ↗

Multiple squamous cell carcinomas of the head and neck show different phenotypes of allelic loss patterns suggesting different clonal origin of carcinogenesis.Semantic proximity Read ↗

A dynamic oral cancer field: unraveling the underlying biology and its clinical implication.Semantic proximity Read ↗

Second primary tumors and field cancerization in oral and oropharyngeal cancer: Molecular techniques provide new insights and definitionsSemantic proximity Read ↗

Centrosome hyperamplification in head and neck squamous cell carcinoma: a potential phenotypic marker of tumor aggressiveness.Semantic proximity Read ↗

Establishment and Genetic Landscape of Precancer Cell Model Systems from the Head and Neck Mucosal LiningSemantic proximity Read ↗

Susceptibility of Multiple Primary Cancers in Patients With Head and Neck Cancer: Nature or Nurture?Semantic proximity Read ↗

A genetic progression model of oral cancer: current evidence and clinical implications.Semantic proximity Read ↗

Profiling clonality and progression in multiple premalignant and malignant oral lesions identifies a subgroup of cases with a distinct presentation of squamous cell carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.