Sequence analysis of the 2nd intron revealed common sequence motifs providing the means for a unique sequencing based typing protocol of the HLA-A locus.

doi:10.1111/j.1399-0039.1996.tb02521.x

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Article

Sequence analysis of the 2nd intron revealed common sequence motifs providing the means for a unique sequencing based typing protocol of the HLA-A locus.

Tissue antigens - 1 Feb 1996

Blasczyk R, Wehling J, Weber M, Salama A

Abstract excerpt

We here present a sequencing strategy for the HLA-A locus which is generally applicable for all HLA class I genes. The typing strategy is based on a group-specific amplification according to the serologically defined antigens. The PCR products carry the typing-relevant polymorphic regions of the...

Topics

Alleles
Base Sequence
DNA
DNA Primers
HLA-A Antigens
Humans
Introns
Molecular Sequence Data
Sequence Analysis

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