Article
Full-length extension of HLA allele sequences by HLA allele-specific hemizygous Sanger sequencing (SSBT).
Human immunology - 1 Nov 2018
Voorter Christina E M, Matern Ben, Tran Thuong Hien, Fink Annette, Vidan-Jeras Blanka, Montanic Sendi, Fischer Gottfried, Fae Ingrid, de Santis Dianne, Whidborne Rebecca, Andreani Marco, Testi Manuela, Groeneweg Mathijs, Tilanus Marcel G J
Abstract excerpt
The gold standard for typing at the allele level of the highly polymorphic Human Leucocyte Antigen (HLA) gene system is sequence based typing. Since sequencing strategies have mainly focused on identification of the peptide binding groove, full-length sequence information is lacking for >90% of the HLA alleles. One of the goals of the 17th IHIWS workshop is to establish full-length sequences for as many HLA...
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