Article
A PCR-SSP method to specifically select HLA-A*0201 individuals for immunotherapeutic studies.
Tissue antigens - 1 Jun 2000
Gatz S A, Pohla H, Schendel D J
Abstract excerpt
HLA-A*0201 is an important restriction element for peptide presentation to T cells in disease and cancer. Mutation studies and analyses using cytotoxic T lymphocytes have shown the functional relevance of subtype-specific differences in HLA-A2 molecules for peptide binding and T-cell receptor recognition. Therefore, many immunotherapeutic studies need to accurately select HLA-A*0201-positive individuals. We...
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