[Allele losses in squamous cell carcinomas of the larynx].

doi:10.1055/s-2007-997531

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Article

[Allele losses in squamous cell carcinomas of the larynx].

Laryngo- rhino- otologie - 1 Jan 1996

Bockmühl U, Petersen I, Dietel M

Abstract excerpt

BACKGROUND: Loss of function of tumor suppressor genes is important in the origin and progression of malignant tumors. Analysis for loss of heterozygosity (LOH) in tumors has been used to detect chromosomal regions that could harbor these genes. METHODS: We investigated 30 paired samples of tumor...

Topics

Aged
Aged, 80 and over
Alleles
Carcinoma, Squamous Cell
Cell Transformation, Neoplastic
Chromosome Aberrations
DNA, Neoplasm
Female
Heterozygote
Humans
Laryngeal Neoplasms
Larynx
Male
Middle Aged

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