Article
[Allelic loss on chromosome 3p21-26 in nasopharyngeal carcinoma].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Jul 1998
Deng L, Jiang N, Tan G
Abstract excerpt
OBJECTIVE: To determine the frequency and extent of loss of heterozygosity (LOH) on chromosome 3p in nasopharyngeal carcinoma (NPC). METHODS: Sixteen loci on chromosome bands 3p21-26 in 24 tumors was studied by using microsatellite analysis. RESULTS: LOH on 3p21-26 was found in 16 of 24 tumors (66.7%). The highest frequency of the allelic loss was found in two adjacent loci D3S1620(50%, 11/22) and D3S1560 (50%,...
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