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Article

Allele-specific chromosome 3p deletions occur at an early stage in the pathogenesis of lung carcinoma.

JAMA - 15 Feb 1995

Hung J, Kishimoto Y, Sugio K, Virmani A, McIntire D D, Minna J D, Gazdar A F

Abstract excerpt

BACKGROUND: Deletions in the short arm of chromosome 3 (3p) are present in most lung carcinomas. OBJECTIVE: To investigate the role of these chromosome 3p deletions in the pathogenesis of non-small cell lung carcinomas. DESIGN: Seven archival, paraffin-embedded, surgically resected lung cancer specimens were studied. Fifty precisely identified malignant and preneoplastic lesions present in bronchi, bronchioles,...

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PMID: 7837389

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Allele-specific chromosome 3p deletions occur at an early stage in the pathogenesis of lung carcinoma.PMID 7837389Read ↗

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