Imprinted expression and methylation of the mouse H19 gene are conserved in extraembryonic lineages.

doi:10.1002/(SICI)1520-6408(1998)23:2<111::AID-DVG3>3.0.CO;2-9

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Article

Imprinted expression and methylation of the mouse H19 gene are conserved in extraembryonic lineages.

Developmental genetics - 1 Jan 1998

Davis T L, Tremblay K D, Bartolomei M S

Abstract excerpt

The imprinted H19 gene is hypomethylated on the active maternal allele and hypermethylated on the repressed paternal allele in the somatic tissues of mice and humans. We previously demonstrated that the paternal-specific methylation of a 2 kb region located between -2 and -4 kb relative to the st...

Topics

Alleles
Animals
Cell Lineage
Crosses, Genetic
DNA Methylation
Female
Gene Expression Regulation, Developmental
Genomic Imprinting
Male
Mice
Muscle Proteins
Mutagenesis
Organ Specificity
RNA, Long Noncoding
RNA, Untranslated
Yolk Sac

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