Article
The H19 methylation imprint is erased and re-established differentially on the parental alleles during male germ cell development.
Human molecular genetics - 22 Nov 2000
Davis T L, Yang G J, McCarrey J R, Bartolomei M S
Abstract excerpt
Differences in DNA methylation distinguish the maternal and paternal alleles of many imprinted genes. Allele-specific methylation that is inherited from the gametes and maintained throughout development has been proposed as a candidate imprinting mark. To determine how methylation is established in the germline, we have analyzed the allelic methylation patterns of the maternally expressed, paternally methylated...
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