Epigenetic mechanisms underlying the imprinting of the mouse H19 gene.

doi:10.1101/gad.7.9.1663

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Article

Epigenetic mechanisms underlying the imprinting of the mouse H19 gene.

Genes & development - 1 Sept 1993

Bartolomei M S, Webber A L, Brunkow M E, Tilghman S M

Abstract excerpt

The expression of the H19 gene is governed by parental imprinting in mammals. H19, an unusual gene encoding an RNA with no known function, is exclusively expressed from the maternal chromosome. In mouse, it lies 90 kb downstream from the Igf2 gene, which encodes a fetal-specific growth factor, in...

Topics

Alleles
Animals
Chromatin
DNA
Embryo, Mammalian
Enhancer Elements, Genetic
Female
Genes
Male
Methylation
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Polymorphism, Restriction Fragment Length
Promoter Regions, Genetic
RNA
Spermatozoa
Stem Cells

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