Chromosome 11p15.5 regional imprinting: comparative analysis of KIP2 and H19 in human tissues and Wilms' tumors.

doi:10.1093/hmg/5.8.1101

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Article

Chromosome 11p15.5 regional imprinting: comparative analysis of KIP2 and H19 in human tissues and Wilms' tumors.

Human molecular genetics - 1 Aug 1996

Chung W Y, Yuan L, Feng L, Hensle T, Tycko B

Abstract excerpt

The imprinted H19 gene is frequently inactivated in Wilms' tumors (WTs) either by chromosome 11p15.5 loss of heterozygosity (LOH) or by hypermethylation of the maternal allele and it is possible that there might be coordinate disruption of imprinting of multiple 11p15.5 genes in these tumors. To...

Topics

Adult
Alleles
Azacitidine
Base Sequence
Cell Line
Child
Chromosomes, Human, Pair 11
Cyclin-Dependent Kinase Inhibitor p57
DNA Methylation
DNA Modification Methylases
DNA Primers
Decitabine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Enzyme Inhibitors

Female

Fetus

Gene Expression Regulation

Genes, Tumor Suppressor

Genomic Imprinting

Source

Open in PubMed

Identifiers

PMID: 8842727
DOI: 10.1093/hmg/5.8.1101

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8842727-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Chromosome 11p15.5 regional imprinting: comparative analysis of KIP2 and H19 in human tissues and Wilms' tumors.PMID 8842727Read ↗

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