Article
Biallelic expression of HRAS and MUCDHL in human and mouse.
Human genetics - 1 Apr 2003
Goldberg Michael, Wei Michelle, Yuan Luwa, Murty Vundavalli V, Tycko Benjamin
Abstract excerpt
At least eight genes clustered in 1 Mb of DNA on human chromosome (Chr) 11p15.5 are subject to parental imprinting, with monoallelic expression in one or more tissues. Orthologues of these genes show conserved linkage and imprinting on distal Chr 7 of mice. The extended imprinted region has a bipartite structure, with at least two differentially methylated DNA elements (DMRs) controlling the imprinting of two...
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