Article
T cell immunodeficiency involved in pathogenicity of attenuated MHV3 mutants.
Advances in experimental medicine and biology - 1 Jan 1995
Lamontagne L, Page C, Martin J P
Abstract excerpt
Viral pathogenicity results when there is an imbalance between viral replication and the host's immune defenses. The immune system plays and important role in the outcome of an acute disease induced by the mouse hepatitis virus type 3 (MHV3). Of use in the study of the role of viral properties involved in its pathogenicity is the attenuated escape mutants. We reported that two MHV3 escape mutants were attenuated...
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