Article
Role of CTL mutants in demyelination induced by mouse hepatitis virus, strain JHM.
Advances in experimental medicine and biology - 1 Jan 1998
Perlman S, Pewe L
Abstract excerpt
Mouse hepatitis virus, strain JHM (MHV-JHM) is a well described cause of demyelination. C57B1/6 (B6) mice infected at the suckling stage in the presence of protective antibodies remain asymptomatic initially but later develop clinical disease (hindlimb paralysis). Infectious virus can be isolated...
Topics
- Animals
- Coronavirus Infections
- Demyelinating Diseases
- Mice
- Murine hepatitis virus
- Mutation
- T-Lymphocytes, Cytotoxic
