Article
Role of CTL mutants in demyelination induced by mouse hepatitis virus, strain JHM.
Advances in experimental medicine and biology - 1 Jan 1998
Perlman S, Pewe L
Abstract excerpt
Mouse hepatitis virus, strain JHM (MHV-JHM) is a well described cause of demyelination. C57B1/6 (B6) mice infected at the suckling stage in the presence of protective antibodies remain asymptomatic initially but later develop clinical disease (hindlimb paralysis). Infectious virus can be isolated from these mice. Recently, two MHV-specific target epitopes for cytotoxic CD8 T cells have been identified in B6 mice....
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